Platelet rich stroma treatment for knee arthritis India

Platelet rich stroma treatment knee arthritis India

A 75 year old lady with symptoms of knee locking obtained relief after Platelet rich stroma treatment in Chennai. Listen to her testimonial in this video. Dr.A.K.Venkatachalam provides this treatment in Chennai. Although this is a short term honest statement of pain relief by this patient, this study describes the mid term result of SVF treatment at five years. The conclusion in this paper is that 60 percent of patients have acceptable pain relief at five years. This might seem to be sufficient justification for undergoing this procedure which might seem expensive initially.

What is Platelet rich stroma?

Platelet-rich stroma (PRS) is a type of orthobiologic treatment that combines two different types of biological materials: platelet-rich plasma (PRP) and stromal vascular fraction (SVF).

What is PRP?

PRP is a concentrated solution of platelets and growth factors that are derived from a patient’s own blood. It is often used in regenerative medicine to promote tissue healing and reduce inflammation. A concentration of 4 x baseline value of platelets is desirable. PRP provides the growth factors which enable SVF cells to adhere.

What is SVF?

SVF is a mixture of stem cells, immune cells, and other regenerative cells that are derived from adipose tissue (fat). SVF is also known to have regenerative properties. Cells in SVF possess signalling effects. That is they stimulate resident cells within the joint to multiply and produce cartilage matrix. This property of SVF is known as “Paracrine effect” ( See point 4 below)

Stromal vascular fraction (SVF) has been suggested as a potential treatment for knee osteoarthritis due to its ability to combat the inflammatory causes of the condition. SVF contains a mixture of various cells, including mesenchymal stem cells (MSCs), immune cells, and other regenerative cells, which work together to address inflammation and promote tissue healing.

  1. Anti-inflammatory properties: MSCs within SVF have been found to possess anti-inflammatory properties. They can modulate the immune response and reduce the production of pro-inflammatory molecules, such as cytokines and chemokines. By suppressing inflammation, SVF can help alleviate pain and reduce the progression of knee osteoarthritis.
  2. Immune modulation: SVF contains immune cells, including regulatory T cells (Tregs), which play a role in immune regulation. Tregs can suppress the activity of other immune cells that contribute to inflammation. This immune modulation by SVF can help control the inflammatory response in the knee joint affected by osteoarthritis.
  3. Growth factor secretion: SVF cells, including MSCs, have the ability to secrete various growth factors, which can aid in tissue repair and regeneration. These growth factors promote the proliferation and differentiation of cells involved in cartilage and tissue repair, contributing to the healing process in the knee joint affected by osteoarthritis.
  4. Paracrine effects: SVF cells secrete factors that exert paracrine effects, meaning they influence nearby cells. These paracrine factors can have anti-inflammatory effects and promote tissue regeneration, helping to combat the inflammatory causes of knee osteoarthritis. The resident cartilage forming cells produce cartilage matrix. Cartilage is the weight bearing cushioning material at the ends of bones. Regeneration of cartilage has been observed in this paper.

In PRS treatment, a small amount of adipose tissue is harvested from the patient and processed to extract SVF. The PRP is then combined with the SVF to create the PRS solution. This PRS solution is then injected into the area of injury or degeneration to promote tissue regeneration and repair.

If you wish to get this treatment for yourself, get in touch by filling the contact form in the home page.

 

 

SVF treatment knee arthritis Chennai India

SVF treatment knee arthritis Chennai India

Are you suffering from Knee osteoarthritis in Chennai India? If so, you may be wondering if there is an available alternative treatment to knee replacement that can help you. In this video, we will hear from this patient about the reason why she chose SVF treatment. She had seen the failure of knee replacements done elsewhere in other patients This treatment is available in Chennai India and can help you become pain-free!

What is SVF treatment?

Stromal vascular fraction treatment or SVF treatment knee arthritis Chennai India is a new treatment for knee arthritis. It avoids the risks associated with a knee replacement. It is done as a daycare procedure.

In this procedure, the surgeon removes fat from your body by liposuction and processes it in a centrifuge in the operating room. The processed fat contains a mixture of cells, vascular stroma, growth factors, and others. It is then mixed with PRP and then injected into the knee. The procedure takes about an hour for one knee. Patients are able to return home within a few hours. They may feel some discomfort on the first day but the pain will improve.

How is it better than bone marrow treatment?

SVF is derived from fat. It is superior to bone marrow. See this post to know more about the advantages of fat over bone marrow.

Is it better than knee replacement?

According to this lady, she had seen many failures of knee replacement done elsewhere. Other patients have also stated that a knee replacement procedure with its necessary physiotherapy is an ordeal.

What is the evidence for SVF treatment?

SVF treatment is a safe procedure with proven results. A double-blind study has confirmed the effectiveness of SVF therapy. There are other studies that vouch for fat stem cell treatment in knee osteoarthritis. My longest follow-up for stem cell treatment for knee arthritis is seven years. See this video 

In this video, this lady states that she had seen many successes of SVF treatment in India by Dr.A.K.Venkatachalam

SVF treatment India

SVF treatment Knee osteo-arthritis India

After getting SVF biologic treatment to both her knees for osteo-arthritis, this 52 year old university professor was able to walk without pain on the same day, climb stairs on the next, cook, dust and walk within a few days; all this without taking a single painkiller. She is very happy with this knee replacement alternative nine months after her treatment in Chennai. So can you too be! Visit www.orthobiologicsurgeryindia.com