Platelet-Rich Stroma Treatment for Chondromalacia Patella India

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Platelet-Rich Stroma (PRS) Treatment for Chondromalacia Patella

Chondromalacia Patella, often referred to as “runner’s knee,” is a condition where the cartilage on the underside of the patella (kneecap) deteriorates and softens. This can lead to pain, swelling, and difficulty moving the knee.

Diagnosis-

3 T MRI is the best diagnostic modality.

Traditional treatments include rest, physical therapy, and anti-inflammatory medications. However, a newer, promising treatment option is Platelet-Rich Stroma (PRS) therapy.

What is PRS Therapy?

PRS therapy involves using the patient’s own blood to promote healing. The process begins with drawing a small amount of blood from the patient. This blood is then placed in a centrifuge, which spins it at high speeds to separate the platelets and stromal cells from other blood components. The concentrated platelets and stromal cells, which are rich in growth factors, are then injected into the affected area of the knee.

How Does PRS Work for Chondromalacia Patella?

The growth factors in the platelets and stromal cells help to accelerate the body’s natural healing process. When injected into the damaged cartilage, PRS can reduce inflammation, promote tissue repair, and alleviate pain. This makes it an attractive option for those who have not found relief with conventional treatments.

Benefits of PRS Therapy

  1. Minimally Invasive: PRS therapy is a minimally invasive procedure that involves only a blood draw and , a fat aspiration and injection, reducing the risk of complications.
  2. Natural Healing: Since PRS uses the patient’s own blood and stem cells, there is no risk of allergic reactions or infections.
  3. Effective Pain Relief: Many patients experience significant pain relief and improved function after PRS therapy.

PRS Therapy in India

In India, PRS therapy is becoming increasingly popular for treating conditions like chondromalacia patella. Dr.A.K.Venkatachalam offers Platelet rich stroma (PRS) treatment for knee osteoarthritis which is the ultimate result of chondromalacia patella is not treated. PRS treatment has also helped the young patient in the attached video and also other young persons

Conclusion

Platelet-Rich Stroma therapy is a promising treatment for chondromalacia patella, offering a minimally invasive and natural approach to healing. With its potential to reduce pain and promote tissue repair, PRS therapy is an option worth considering for those suffering from this painful condition.

See this video in which a happy father narrates the relief that his son got after PRS or SVF treatment for chondromalacia patella

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SVF treatment knee arthritis Chennai, 5 month review

SVF treatment knee arthritis Chennai, 5 month review

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Listen to a patient’s review at 5 months for SVF treatment of knee arthritis. Her condition has tremendously improved. She has improvement of pain score, walking distance, stiffness, gait and collateral improvement in other joints as well.

This lady has a lot of improvement in her condition after five months. Her pain is much less, her stiffness has gone, her gait is straight, and her overall function is better.

What is the SVF and PRP treatment that this lady underwent?

Combined SVF and PRP treatment, also known as platelet-rich stroma (PRS) treatment, is a regenerative medicine therapy that uses two components derived from the patient’s own body to treat knee osteoarthritis. Stromal vascular fraction (SVF): This is a collection of cells isolated from fat tissue, such as the abdomen or thighs. SVF contains stem cells, endothelial cells, pericytes, and immune cells. These cells have the potential to differentiate into various cell types and promote tissue repair. Platelet-rich plasma (PRP): This is a concentrated preparation of platelets obtained from the patient’s blood. Platelets contain growth factors and cytokines that promote tissue healing and regeneration.

How is it done?

PRS treatment is a minimally invasive procedure that typically takes about an hour. Here’s a general overview of the steps involved: A small amount of fat tissue is harvested from the patient using liposuction. The fat tissue is processed to isolate the SVF. Blood is drawn from the patient and centrifuged to create PRP. The SVF and PRP are combined to create the PRS solution. The PRS solution is injected into the affected knee joint under ultrasound guidance.

Benefits –

PRS treatment is a relatively new therapy, and more research is needed to confirm its long-term efficacy. However, some studies have shown that it may be effective in reducing pain and improving function in patients with knee osteoarthritis. The potential benefits of PRS treatment include: Reduced pain and inflammation Improved joint function Increased range of motion Slowed progression of osteoarthritis Risks and side effects PRS treatment is generally considered to be safe. However, there are some potential risks and side effects associated with the procedure, such as Pain at the injection site Infection Bleeding Allergic reactions

Is it right for me?

If you are considering PRS treatment for knee osteoarthritis, it is important to talk to your doctor to discuss the potential benefits and risks and to see if it is right for you. Dr. A.K. Venkatachalam offers consultation at Chennai Meenakshi multi-specialty hospital by appointment. Book yours today. Call the hospital at 044 42938938. PRS treatment is not a cure for osteoarthritis, but it may be a viable option for people who are looking for a non-surgical treatment to manage their pain and improve their quality of life. Here are some additional things to keep in mind: PRS treatment is not covered by most insurance plans. There is limited scientific evidence on the long-term efficacy of PRS treatment. It is important to choose a qualified and experienced provider to perform the procedure.

I hope this information is helpful. Please let me know if you have any other questions. #SVFtreatment #kneearthritis #PRStreatmentchennai

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Platelet-rich stroma treatment knee arthritis Chennai

Platelet-rich stroma treatment knee arthritis Chennai

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This gentleman sought Platelet-rich stroma treatment knee arthritis Chennai from Dr.A.K.Venkatchalam. Although he had advanced grade 4 arthritis in both knees, the treatment provided pain relief after 3 days.

Osteoarthritis (OA) of the knee, a condition where the protective cartilage wears away, can be a source of chronic pain and limit mobility. While traditional treatments like medication and physical therapy offer relief, they don’t address the root cause. Enter platelet-rich stroma (PRS) treatment, a promising new approach that harnesses the body’s own healing potential.

What is Platelet-rich stroma treatment knee arthritis Chennai (PRS)?

PRS is a minimally invasive procedure that combines two powerful components:

  • Platelet-rich plasma (PRP): Concentrated platelets from your blood, rich in growth factors that promote tissue repair and regeneration.
  • Stromal vascular fraction (SVF): A collection of stem cells and other healing cells derived from your fat tissue.

How does PRS work for knee OA?

When injected into the knee joint, PRS delivers a concentrated dose of healing factors:

  • Reduced inflammation: SVF’s stem cells have anti-inflammatory properties, calming the pain and joint damage.
  • Cartilage regeneration: Growth factors in PRP stimulate cartilage growth and repair damaged tissue.
  • Improved lubrication: PRS promotes the production of synovial fluid, the lubricant that keeps your joints moving smoothly.

Benefits of PRS for knee OA:

  • Pain relief: Studies show significant pain reduction after PRS treatment, improving quality of life.
  • Improved function: Patients experience increased mobility and flexibility, allowing for better daily activities.
  • Potential to delay surgery: PRS may offer a non-surgical option for managing OA, potentially postponing or even avoiding joint replacement.
  • Minimally invasive: The procedure is relatively quick and well-tolerated, with minimal downtime. experienced in PRS therapy to discuss if it’s right for you.
  • Conclusion:

Platelet-rich stroma therapy is a cutting-edge treatment for knee osteoarthritis that utilizes the patient’s adipose (fat) tissue and Platelet-rich plasma (PRP) to promote healing and reduce pain.

It is done as an outpatient procedure and takes about 2 hours as stated by this patient. He went home soon after and was able to walk without any pain using minimal support.

Plaelet-rich stroma treatment is a safer alternative to knee replacement as said by this patient.

If you want to see more testimonials about biologic treatments for knee arthritis, and shoulder problems, visit Testimonials | Ortho Biologic Surgery Indiahttps://orthobiologicsurgeryindia.com/testimonials-stem-cell-treatment-knee-arthritis/

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Stem cell treatment knee arthritis Chennai

Stem cell treatment knee arthritis Chennai

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Stem cell treatment knee arthritis Chennai. See this patient’s testimonial

Fat-derived stem cell treatment for knee osteoarthritis is a relatively new and promising therapy that is being investigated as a potential way to regenerate damaged cartilage and alleviate pain.

What are stem cells?

Stem cells are undifferentiated cells that have the ability to divide and give rise to specialized cells. They can be found in various parts of the body, including bone marrow, adipose tissue (fat), and umbilical cord blood. Adipose-derived stem cells (ADSCs) are particularly attractive for stem cell therapy because they are relatively easy to harvest and have the potential to differentiate into multiple cell types, including cartilage cells.

How does fat-derived stem cell treatment for knee osteoarthritis work?

The fat-derived stem cells are harvested from the patient’s own body, typically from the abdomen or thigh. The cells are then processed and concentrated in a laboratory. The concentrated stem cells are then injected into the knee joint. Once injected into the knee, the stem cells are believed to have several potential therapeutic effects: Reduce inflammation: Stem cells release anti-inflammatory factors that can help to reduce pain and swelling. Promote cartilage repair: Stem cells may differentiate into cartilage cells and help to repair damaged cartilage. Improve lubrication: Stem cells may help to produce synovial fluid, which lubricates the joint.

What is the evidence for fat-derived stem cell treatment for knee osteoarthritis?

There is growing evidence that fat-derived stem cell treatment is safe and effective for knee osteoarthritis. However, more research is needed to determine the long-term efficacy of this treatment. A 2021 study published in the journal Stem Cell Research & Therapy found that intra-articular injection of ADSCs was safe and effective in reducing pain and improving function in patients with knee osteoarthritis. A 2020 study published in the journal Knee Surgery, Sports Traumatology, Arthroscopy found that intra-articular injection of ADSCs with or without platelet-rich plasma was effective in decreasing pain and symptoms in knee osteoarthritis.

What are the risks and side effects of fat-derived stem cell treatment for knee osteoarthritis?

The most common side effects of fat-derived stem cell treatment for knee osteoarthritis are injection site pain and swelling. Overall, fat-derived stem cell treatment for knee osteoarthritis is a promising new therapy that has the potential to improve symptoms and slow the progression of the disease.

Why is performing this treatment in Chennai?

Dr. Venkatacham is a pioneer in regenerative medicine in India and has extensive experience with SVF therapy. His institute in Chennai is one of the leading centers for the treatment

Where can you get this treatment?

Contact the doctor by filling a form or call the hospital to fix an appointment.

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Suffering from knee arthritis in Chennai? Try PRS treatment

Suffering from knee arthritis in Chennai? Try PRS treatment

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Are you suffering from knee arthritis in Chennai? Try PRS treatment. Watch this video to see how PRS can help you get rid of knee pain and improve your quality of life. PRS treatment is becoming an alternative to total knee replacement among many due to its non-invasiveness, quick results, cost, and durable results. You can see the pre-operative state and post-operative recovery. PRS is a minimally invasive procedure that uses the patient’s stem cells and growth factors to regenerate damaged cartilage and reduce inflammation. The patient was able to walk within a few hours after the treatment with minimal assistance and no pain.

You can see testimonials of more patients here 

 

If you are interested in PRS treatment for knee arthritis, please contact Dr. A.K. Venkatachalam at Madras Joint Replacement Centre. He is one of the leading experts in regenerative medicine and joint replacement surgery in India. Visit his website to learn more about his services and testimonials from his patients.

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Evidence for Stem cell treatment knee osteoarthritis India

Evidence for Stem cell treatment knee osteoarthritis Chennai

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See the evidence for Stem cell treatment of knee osteoarthritis Chennai discussed in this video. I read from a recently published paper in the Journal of Arthritis Research.

Here’s the video. If interested learn more at www.orthobiologicsurgeryindia.com. 

I perform knee replacements, and Orthobiologic procedures.

Stromal vascular fraction (SVF) is a concentrated cell-packed portion of adipose tissue that has been used to treat knee osteoarthritis (OA) 1. SVF is known for its anti-inflammatory characteristics and has been shown to decrease pain and improve function in patients with knee OA 1 2.

In a single-center, non-randomized, phase I/II trial, 33 patients with KL (III) knee osteoarthritis were evaluated. The study aimed to evaluate the improvement in knee pain, function, and cartilage restoration. The results showed that joints treated with SVF provided a better quality of life to patients 1.

Other frequently found interventions include cultured adipose-derived stem cells (ADSCs), and the micronized/microfragmented adipose tissue-stromal vascular fraction (MAT-SVF) 1. Clinical data reported that joints treated with MAT-SVF provided a better quality of life to patients 1.The mechanism of action of SVF is also not fully understood. However, the current hypothesis indicates a direct adherence and integration with the degenerative host tissue, and/or trophic effects resulting from the secretome of constituent cells 1.

In conclusion, there is evidence of efficacy in the use of stromal vascular fraction and related therapy for the treatment of osteoarthritis of the knee. However, more research and clinical patient follow-up are needed to determine the proper place of these therapies in the treatment of osteoarthritis of the knee 1.

Source(s)

1. Stromal Vascular Fraction for Osteoarthritis of the Knee Regenerative …

2. Cartilage lesion size and number of stromal vascular fraction (SVF …

3. Autologous Adipose-Derived Tissue Stromal Vascular Fraction (AD-tSVF …

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Stem cell treatment knee arthritis Chennai

Stem cell treatment knee arthritis Chennai

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See the impressive result provided by Stem cell treatment knee arthritis Chennai in this man. He is able to walk without pain. He chose Stem cell treatment or PRS treatment instead of knee replacement. The reason was two botched-up knee replacement operations amongst his family members.

Adipose stem cell treatment is a type of regenerative medicine that uses fat tissue as a source of mesenchymal stem cells (MSCs) to treat knee osteoarthritis (OA). MSCs are multipotent cells that can differentiate into various types of cells, such as cartilage, bone, and muscle. They also have anti-inflammatory and immunomodulatory properties that can promote healing and reduce pain. Adipose stem cell treatment involves harvesting fat tissue from the patient’s own body, usually from the abdomen or thigh, and processing it to isolate the MSCs. The MSCs are then injected into the affected knee joint, where they can potentially regenerate the damaged cartilage and improve joint function.

There are several clinical trials and studies that have evaluated the safety and efficacy of adipose stem cell treatment for knee OA. Some of the results are summarized below:

These studies suggest that adipose stem cell treatment is a promising option for knee OA treatment, especially for elderly patients who have limited options for surgery or pharmacotherapy.

Now watch his performance 5 days after the procedure. He is able to walk comfortably on a slope.

If you want to see more testimonials visit my website 

If you are interested in this procedure, fill up the contact form on my website

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Platelet Rich Stroma Therapy for Knee Osteoarthritis

Exploring Platelet Rich Stroma Therapy for Knee Osteoarthritis

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In this article i will elaborate how Platelet rich stroma treatment can stem the pain of Osteoarthritis.

You will hear from an eighty year old lady in Tamil and her son in English in the video at first.

Do you wish to learn about this latest alternative to knee replacement?

Platelet-rich plasma (PRP) treatment is a type of orthobiologic treatment that has been used to treat knee osteoarthritis in India. It  combines two different types of biological materials: platelet-rich plasma (PRP) and stromal vascular fraction (SVF).

What is PRP?

PRP is a concentrated solution of platelets and growth factors that are derived from a patient’s own blood. It is often used in regenerative medicine to promote tissue healing and reduce inflammation.

What is SVF?

SVF, on the other hand, is a mixture of stem cells, immune cells, and other regenerative cells that are derived from adipose tissue (fat). SVF is also known to have regenerative properties and is commonly used in stem cell therapy.

In PRS treatment, a small amount of adipose tissue is harvested from the patient and processed to extract the SVF. The PRP is then combined with the SVF to create the PRS solution. This PRS solution is then injected into the area of injury or degeneration to promote tissue regeneration and repair

How does stromal vascular fraction combat the inflammatory cause of knee osteoarthritis?

Stromal vascular fraction (SVF) is believed to combat the inflammatory cause of knee osteoarthritis through its regenerative properties. SVF contains a mixture of different cell types, including stem cells and immune cells, which work together to modulate inflammation and promote tissue repair.

  1. Anti-Inflammatory Effects: Some of the cells present in SVF, such as mesenchymal stem cells, have anti-inflammatory properties. When injected into the knee joint, these cells can help suppress the release of pro-inflammatory molecules and cytokines that contribute to the inflammation seen in osteoarthritis. By reducing inflammation, SVF may help alleviate pain and slow down the progression of the disease.
  2. Tissue Repair and Regeneration: SVF contains cells that have the ability to differentiate into various cell types, including cartilage-producing cells. In knee osteoarthritis, the protective cartilage cushioning the joint gradually wears away. SVF injections may promote the growth of new cartilage-like tissue, contributing to joint repair and improved function.
  3. Immunomodulation: SVF contains immune cells that play a role in regulating the immune response. These cells can help create an environment that is less hostile to the joint, reducing the immune system’s attack on healthy tissue and further decreasing inflammation.
  4. Growth Factors and Cytokines: SVF is rich in growth factors and cytokines, which are signaling molecules that promote cell growth, differentiation, and healing. These factors can stimulate the body’s natural healing processes and support the repair of damaged tissues. If you desire to undergo this latest treatment, seek an appointment with Dr.A.K.Venkatachalam by filling out the contact form in www.orthobiologicsurgeryindia.com

 

 

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Platelet rich stroma treatment for knee arthritis India

Platelet rich stroma treatment knee arthritis India

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A 75 year old lady with symptoms of knee locking obtained relief after Platelet rich stroma treatment in Chennai. Listen to her testimonial in this video. Dr.A.K.Venkatachalam provides this treatment in Chennai. Although this is a short term honest statement of pain relief by this patient, this study describes the mid term result of SVF treatment at five years. The conclusion in this paper is that 60 percent of patients have acceptable pain relief at five years. This might seem to be sufficient justification for undergoing this procedure which might seem expensive initially.

What is Platelet rich stroma?

Platelet-rich stroma (PRS) is a type of orthobiologic treatment that combines two different types of biological materials: platelet-rich plasma (PRP) and stromal vascular fraction (SVF).

What is PRP?

PRP is a concentrated solution of platelets and growth factors that are derived from a patient’s own blood. It is often used in regenerative medicine to promote tissue healing and reduce inflammation. A concentration of 4 x baseline value of platelets is desirable. PRP provides the growth factors which enable SVF cells to adhere.

What is SVF?

SVF is a mixture of stem cells, immune cells, and other regenerative cells that are derived from adipose tissue (fat). SVF is also known to have regenerative properties. Cells in SVF possess signalling effects. That is they stimulate resident cells within the joint to multiply and produce cartilage matrix. This property of SVF is known as “Paracrine effect” ( See point 4 below)

Stromal vascular fraction (SVF) has been suggested as a potential treatment for knee osteoarthritis due to its ability to combat the inflammatory causes of the condition. SVF contains a mixture of various cells, including mesenchymal stem cells (MSCs), immune cells, and other regenerative cells, which work together to address inflammation and promote tissue healing.

  1. Anti-inflammatory properties: MSCs within SVF have been found to possess anti-inflammatory properties. They can modulate the immune response and reduce the production of pro-inflammatory molecules, such as cytokines and chemokines. By suppressing inflammation, SVF can help alleviate pain and reduce the progression of knee osteoarthritis.
  2. Immune modulation: SVF contains immune cells, including regulatory T cells (Tregs), which play a role in immune regulation. Tregs can suppress the activity of other immune cells that contribute to inflammation. This immune modulation by SVF can help control the inflammatory response in the knee joint affected by osteoarthritis.
  3. Growth factor secretion: SVF cells, including MSCs, have the ability to secrete various growth factors, which can aid in tissue repair and regeneration. These growth factors promote the proliferation and differentiation of cells involved in cartilage and tissue repair, contributing to the healing process in the knee joint affected by osteoarthritis.
  4. Paracrine effects: SVF cells secrete factors that exert paracrine effects, meaning they influence nearby cells. These paracrine factors can have anti-inflammatory effects and promote tissue regeneration, helping to combat the inflammatory causes of knee osteoarthritis. The resident cartilage forming cells produce cartilage matrix. Cartilage is the weight bearing cushioning material at the ends of bones. Regeneration of cartilage has been observed in this paper.

In PRS treatment, a small amount of adipose tissue is harvested from the patient and processed to extract SVF. The PRP is then combined with the SVF to create the PRS solution. This PRS solution is then injected into the area of injury or degeneration to promote tissue regeneration and repair.

If you wish to get this treatment for yourself, get in touch by filling the contact form in the home page.

 

 

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