Stem cell treatment knee arthritis Chennai

Stem cell treatment knee arthritis Chennai

Stem cell treatment knee arthritis Chennai
To know what is stem cell treatment for knee arthritis in Chennai, see this video presentation that was delivered at a medical college in Chennai, India three years ago.

What are stem cells?

Cells that are capable of regenerating and replicating and repairing tissues are known as stem cells. They are present in every organ and tissue in the human body like skin, fat, bone marrow, muscle, and heart, everywhere, but they are dormant and can be kicked into action by external methods either by the response to a trauma or by seeding the damaged area with stem cells by injection or open procedure.

This is the classification of stem cells. At the top, you have the totipotent embryonic stem cell which is formed by the fusion of the sperm to the ova. This results in a zygote and the formation of a blastocyst which further differentiates into two cells four-cell then the embryo and the fetus and so on. The totipotent embryonic stem cell gives rise to pluripotent embryonic stem cells which form various tissues. These pluripotent stem cells then give rise to multipotent stem cells which are present in every tissue like the lung, pancreas, heart muscle, red blood cells skin muscle bone marrow, and every other tissue. These are not confined to the mesenchymal space.

How do we isolate stem cells?

We aspirate them from fat by liposuction. Then we manipulate them by centrifuging. Then they are ready for injection.

Stem cell treatment for knee arthritis in India by Dr.A.K.Venkatachalam is done as an outpatient procedure. The patient can return home within a few hours. If spinal anesthesia is given, then discharge takes longer.

The cells can also be isolated like before and sent off to a tissue bank where they are cultured and stored.  By this, their number is expanded to several million and they can be kept in cold storage for longer periods. Certain tissues have got a half-life but some tissues can be stored for a long time.  Their potency decreases after one year. So, when these cells are expanded, they can be returned to the doctor to be re-injected into the patient.

How do I apply or treat damaged areas of cartilage and bone?

See this procedure here 

One can apply it to the cartilage lesion by arthroscopic or open surgery. Here the joint is inspected through an arthroscope, and the area of damage is prepared by shaving and microfracture. Then the cells are made into a paste with fibrin glue and applied to the cartilage lesion. It is shaped with a spatula. Then the joint is put through a range of movements for the glue to set in five minutes. Then the patient is returned to the ward for observation. He/She will remain non-weight bearing and can resume activities full weight-bearing activities after six weeks. This procedure is usually done for single or one or two cartridge lesions.  It does not apply to osteoarthritis wherein I use fluoroscopy or ultrasound guidance for injections.

This is a picture of a slide with seeded chondrocytes

What is the mechanism of action for stem cell treatment of knee arthritis in Chennai?

They have a trophic effect which means they stimulate growth via the secretion of cytokines and growth factors that is when the cells are injected into a joint these growth factors are released and they have the potency or capability of stimulating adjacent cells in the joint to differentiate and form cartilage. These differentiating cells, when stimulated by growth factors, will go ahead and repair areas of damaged cartilage, and limited cartilage repair are possible; not a complete repair in the case of bone on bone.

The cells possess an immune modulatory effect even when injected even from an allergenic source. They erect a barrier between themselves and the native person’s immune system and perform their function without any interference from the destructive and deleterious effects of the immune system like T cells. They have an anti-inflammatory effect. When injected into swollen inflamed joints, they put a brake on inflammation.

After that, there will be continuous improvement.

Antibiotic effect – There is no need for a person to worry when stem cells are injected. They are not at risk of developing a joint infection like septic arthritis of the knee. This is because of the antibiotic effect present in the stem cells themselves.

Self-replication effect- they can replicate as themselves or replication differentiate into further cell types.

They have an anti-aging effect.

What is the role of Stem cells in orthopedic surgery?

The commonest indication is nonunion.  In small non-unions stem cells can be injected which can promote union.

Articular cartilage damage in the knee, shoulder, hip, and ankle joints can be treated with stem cells.  When stem cells are injected into areas of cartilage damage, they can repair cartilage. They can also repair osteochondral defects when inserted in the form of a bone plug.

Osteoarthritis -When there is widespread cartilage of ICRS grade 3 grade or 2, stem cells can help to halt the ongoing osteoarthritis process and lead to limited repair. Patients can get sustained pain relief for a few years.

Avascular necrosis is commonly seen in the hip joint, and it is bilateral. It can result from steroid intake, alcohol, Gaucher’s disease, and deep-sea diving. Blood disorders like sickle cell anemia can result in avascular necrosis. Avascular necrosis in the early stages can be treated with stem cells.

Stem cells can also promote wound dealing like in diabetic ulcers or chronic ulcers

Advantage of fat over bone marrow.

I injected Stromal vascular fraction (SVF) derived from fat.  Earlier I used bone marrow. Fat has several advantages over bone marrow enumerated here.

Bone marrow has fewer stem cells than fat, Fat contains 500 to 2000 times more MSCs than the same volume of bone marrow. Fat cells have the highest proliferation potential, and the cells are younger than bone marrow. in old older people, it may be difficult to obtain cells from the bone marrow because there is osteoporosis. In addition, fat also contains numerous other regenerative cells that are important to the healing process.

A further advantage of fat is that it is less painful. I can aspirate it from the thigh and the patient can go home within a few hours,

Anticoagulants are not required. If you take bone marrow, then you have to treat it immediately with heparin and inject heparin into the bone to prevent it from clotting while being aspirated. This can result in an overdose or leakage of the anticoagulant solution into the adjacent tissue. Bone marrow aspiration from the posterior part of the iliac crest can result in penetration and spread of the heparin in retroperitoneal space, leading to retroperitoneal hematoma.

Cells derived from fat are a better source for articular cartilage repair.

What is the benefit of stem cell treatment for knee arthritis in Chennai?

Some patients have been able to get prolonged pain relief and have postponed knee replacement. The longest follow-up stem cell treatment for the knee is seven years.

See a patient’s testimonial here-

In the short term, they can avoid taking NSAIDs, painkillers, and opioids. They will lead a better quality of life.

So, if you want Stem Cell Treatment for Knee arthritis in Chennai India Dr.A.K.Venkatachalam, click the form, fill it out, and post. You can locate my practice by clicking on this link

Call – 7824003400 or the hospital – 044 42938938

Email -drvenkat@kneeindia.com

 

SVF treatment knee arthritis Chennai India

SVF treatment knee arthritis Chennai India

Are you suffering from Knee osteoarthritis in Chennai India? If so, you may be wondering if there is an available alternative treatment to knee replacement that can help you. In this video, we will hear from this patient about the reason why she chose SVF treatment. She had seen the failure of knee replacements done elsewhere in other patients This treatment is available in Chennai India and can help you become pain-free!

What is SVF treatment?

Stromal vascular fraction treatment or SVF treatment knee arthritis Chennai India is a new treatment for knee arthritis. It avoids the risks associated with a knee replacement. It is done as a daycare procedure.

In this procedure, the surgeon removes fat from your body by liposuction and processes it in a centrifuge in the operating room. The processed fat contains a mixture of cells, vascular stroma, growth factors, and others. It is then mixed with PRP and then injected into the knee. The procedure takes about an hour for one knee. Patients are able to return home within a few hours. They may feel some discomfort on the first day but the pain will improve.

How is it better than bone marrow treatment?

SVF is derived from fat. It is superior to bone marrow. See this post to know more about the advantages of fat over bone marrow.

Is it better than knee replacement?

According to this lady, she had seen many failures of knee replacement done elsewhere. Other patients have also stated that a knee replacement procedure with its necessary physiotherapy is an ordeal.

What is the evidence for SVF treatment?

SVF treatment is a safe procedure with proven results. A double-blind study has confirmed the effectiveness of SVF therapy. There are other studies that vouch for fat stem cell treatment in knee osteoarthritis. My longest follow-up for stem cell treatment for knee arthritis is seven years. See this video 

In this video, this lady states that she had seen many successes of SVF treatment in India by Dr.A.K.Venkatachalam

Stem cell treatment Knee Osteo-arthritis Chennai

Stem cell treatment Knee Osteo-arthritis Chennai

Stem cell treatment Knee Osteo-arthritis Chennai with SVF

Knee osteoarthritis treatment in Chennai India with fat stem cells helped this 65-year-old lady to recover fast. There was no prolonged hospitalization, physiotherapy, or surgical trauma. With travel restrictions being lifted all over the world, she was very eager to travel abroad and meet her grandchildren.

Knee OA is the most usual form of OA worldwide. It affects women more than women. Knee replacement is the standard treatment for end-stage arthritis. However, it necessitates hospitalization and physiotherapy to regain full bending. Nowadays, patients want to recover faster and be able to enjoy life. Hence more patients like this lady are seeking stem cell treatment.

What is SVF treatment?

Stromal vascular fraction treatment or SVF treatment knee arthritis Chennai India is a new treatment for knee arthritis. It avoids the risks associated with a knee replacement. It is done as a daycare procedure.

In this procedure, the surgeon removes fat from your body by liposuction and processes it in a centrifuge in the operating room. The processed fat contains a mixture of cells, vascular stroma, growth factors, and others. It is then mixed with PRP and then injected into the knee. The procedure takes about an hour for one knee. Patients are able to return home within a few hours. They may feel some discomfort on the first day but the pain will improve.

How is it better than bone marrow treatment?

SVF is derived from fat. It is superior to bone marrow. See this post to know more about the advantages of fat over bone marrow.

Is it better than knee replacement?

According to this lady, she had seen many failures of knee replacement done elsewhere. Other patients have also stated that a knee replacement procedure with its necessary physiotherapy is an ordeal.

What is the evidence for SVF treatment?

SVF treatment is a safe procedure with proven results. A double-blind study has confirmed the effectiveness of SVF therapy. There are other studies that vouch for fat stem cell treatment in knee osteoarthritis. My longest follow-up for stem cell treatment for knee arthritis is seven years. See this video 

Stem cell treatment knee arthritis Chennai

Stem cell treatments knee arthritis Chennai India

Stem cell treatments knee arthritis Chennai India by Dr.A.K.Venkatachalam. In this video stem cells are derived from the patient’s own body, prepared, mixed with PRP, and injected into the patient’s knee joint under local anesthesia. The patient can walk normally after the procedure and can return home within a few hours. No keyhole or open surgery is needed. The stem cells injected are more numerous than other sources. See here for more details.

 

Fat stem cell treatment knee arthritis Chennai

This gentleman underwent key hole surgery pf his knee to remove torn meniscal fragments and also fat stem cell treatment. His symptoms of locking was relieved and he felt better 24 hours later. Stem cells derived from fat are more numerous than bone marrow. Fat is an abundantly available tissue and its harvest is minimally invasive. Fat can be removed from the thigh or abdomen under local anesthesia. It is a day care procedure. Patients may experience some discomfort on the day of the procedure but these symptoms disappear the next morning. Visit www.kneeindia.com

Platelet rich plasma is combined with fat derived stromal vascular fraction (SVF) to yield Platelet rich stroma ( PRS). PRP is also administered for shoulder, elbow, heel and other ligament and tendon conditions in addition to knee, hip and shoulder joints. PRP, SVF, Bone marrow injections are orthobiologic conditions performed by Dr.A.K.Venkatachalam 

Knee Cartilage repair India

Knee cartilage regeneration India, patient testimonial for Dr A.K.Venkatachalam after four years

Knee cartilage regeneration India, patient testimonial for Dr A.K.Venkatachalam after four years. In this Infogram you will see proof of cartilage regeneration in India with cellular therapy. By proof I mean the symptoms of the patient had regressed and also the MRI scans showed complete regeneration of cartilage after six months. You will have to scroll to the bottom of the Infogram and then click on the link to see the latest video.

Knee arthritis cellular therapy India

Knee arthritis cellular therapy India -Dr.A.K.Venkatachalam

Knee arthritis cellular therapy India Dr.A.K.Venkatachalam is shown here. The patient is a 72 year old male who had undergone two previous treatments with bone marrow cellular therapy and arthroscopic washout and lavage. Now he has chosen to undergo fat derived cellular therapy because fat is better than bone marrow as it contains more signalling cells. If you want this procedure, email drvenkat@kneeindia.com.

Platelet rich stroma therapy knee osteo-arthritis India

Fat treatment knee osteo-arthritis India- patient testimonial after 3 months

Fat treatment knee osteo-arthritis India three months ago relieved this lady’s pain. As she felt residual leg pain, she was administered a booster dose of platelet rich plasma and felt better afterwards. See her walk independently after the latest procedure. Fat treatment knee osteoarthritis India utilizes the healing potential of your own fat and blood to reduce pain of knee osteo-arthritis. It combines the healing potential of stromal vascular fraction derived from fat and biological molecules derived from platelets; the cells responsible for blood clotting. Limited cartilage regrowth occurs. If you are suffering from knee pain and want to get relief soon, then this may be the right procedure for you. If you want this procedure for your elderly relatives, email me drvenkat@kneeindia.com

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